The Ariston Hotel Milan is located in central downtown Milan. It is five minutes' walk to the Piazza del Duomo and the Via Torino shopping area. The Ariston Hotel Milan is located five minutes from the nearest metro stop.

There are 52 rooms at the Ariston Hotel Milan with modern contemporary furnishings. Rooms have cherry wood accents with air conditioning and ion exchange air filtering, satellite television service, wireless Internet access, and en suite bathrooms. All furnishings are made from recycled goods, and the rooms are cleaned with biologically friendly products.

The Ariston Hotel Milan was the first hotel in Italy to be designed according to bio-architectural criteria. The front desk is open 24 hours a day. A morning breakfast is offered each day with organic fare, and there is a snack bar providing service throughout the day. Meeting rooms can be booked and banqueting support is available. The hotel has a private garage and an open lot for parking for guests with cars and offers bicycles to those without cars free of charge.